IPX066: a new intermediate- and extended-release carbidopa–levodopa formulation

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Population Pharmacodynamics of IPX066: An Oral Extended-Release Capsule Formulation of Carbidopa–Levodopa, and Immediate-Release Carbidopa–Levodopa in Patients With Advanced Parkinson’s Disease

A pharmacodynamic model is presented to describe the motor effects (tapping rate, Unified Parkinson's Disease Rating Scale [UPDRS] Part III, and investigator-rating of ON/OFF, including dyskinesia) of levodopa (LD) in patients with advanced idiopathic Parkinson's disease (PD) treated with immediate-release (IR) carbidopa-levodopa (CD-LD) or an extended-release (ER) formulation of CD-LD (IPX066)...

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ژورنال

عنوان ژورنال: Neurodegenerative Disease Management

سال: 2013

ISSN: 1758-2024,1758-2032

DOI: 10.2217/nmt.13.4